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Lipofundin® and Lipidem® emulsion for infusion

A source of parenteral macronutrient fats

Lipofundin® and Lipidem® provide the macronutrient component in parenteral nutrition regimens. These lipids or fats are a source of energy and are important for absorbing fat-soluble vitamins.


As the innovator of the proven medium chain triglyceride / long chain triglyceride technology, improving patient outcomes is always our focus. Our products can be tailored and adapted to individual patient needs

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Benefits of MCT/LCT over LCT

Clinical benefits when comparing MCT/LCT to 100% LCT:

  • Reduction in post-operative mortality in a sub-group of malnutrition surgical patients without cancer (n=22)2
  • Reduction in post-operative intra-abdominal abscesses in surgical patients (n=22)2
  • The ability to eliminate MCT/LCT was not impaired in cirrhotic patients.
  • Lower levels of plasma bilirubin in in-patients4 and improvements in liver function tests in home patients with inflammatory bowel disease1
  • No adverse cardiopulmonary effects were seen when MCT/LCT was given following valvular heart surgery5
  • Significantly shorter weaning period from mechanical ventilation vs LCT in COPD patients with acute respiratory failure6
  • No significant reduction in neutrophil bacterial killing function7
  • Improvement in nitrogen balance in critically ill patients (n=20)8
  • Greater physicochemical stability9

3-Chamber Bags

B. Braun’s 3-Chamber Bags incorporate our lipid emulsions, Lipofundin® and Lipidem®. Explore the features of our lipid in parenteral nutrition admixture.

Convenience bags
lipid-emulsions-200mg.png
  • 0%

    Coconut Oil

    Medium-chain triglycerides

    Source of readily available energy

  • 0%

    Soya Bean Oil

    Long-chain triglycerides

    Source of EFA’s (essential fatty acids) and energy

  • 0%

    Omega-3-Acid Triglycerides

    From fish oil for the delivery of EPA and DHA

Access the Lipofundin®, Lipidem® and Omeflex® special Prescribing Information via the links below

Interested?


Get in touch with one of our team

Contact Us

XX-WEBLE-05-24 

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to B. Braun Medical Ltd (0800 298 0299). 

XX-WEBNT-05-24

References

  1. Y.A. Carpentier, V. SIderova, J. Bruyns, M. Rubin Long-Term PN and Liver Dysfunction Clinical Nutrition 9 1989;31:31
  2. T. Grau, J. Carlos Ruiz de Adana, S. Zubillaga, S. Fuerte, C. Giron. Randomized Study of Two Different Fat Emulsions in Total Parenteral Nutrition of Malnourished Surgical Patients: Effect on Infectious Morbidity and Mortality Nutr Hosp 2003;18:159-166
  3. S.T. Fan, J. Wong. Metabolic Clearance of a Fat Emulsion Containing Medium-Chain Triglycerides in Cirrhotic Patients. Journal of Parenteral and Enteral Nutrition 1992;16(3):279-283
  4. A.R. Dennison, M. Ball, L.J. Hands, P.J. Crowe, R.M. Watkins, M. Kettleworth. Total Parenteral Nutrition using Conventional and medium Chain triglycerides: Effect on Liver Function tests, Complement, and Nitrogen and Enteral Nutrition 1988;12(1):15-19
  5. F. Fiaccadori, G. Tortorella, G.L. Gonzi, C. Beghi, D. Albertini, S. Pincolini, L. Belli, A. Avogaro. Hemodynamic and respiratory effects of medium-chain and long-chain triglyceride fat emulsions: a prospective randomized study. Rivista Italiana di Nutrizione Parenterale ed Enterale 1997;15(1):6-14
  6. G. Iovinelli, F. Marinaangeli, A. Ciccone, A. Ciccozzi, m. Leonardis, A. Paladini, G. Varrassi. Parenteral nutrition in ventilated patients with chronic obstructive pulmonary disease: long chain vs medium chain triglycerides. Minerva Anestesiol 2007;73:65-76
  7. Dan L Waitzberg, Raquel Bellinati-Pires, Maristela M Salago, Iara P Hypolito, Gloria MDD Colleto, Osmar Yagi, Elisa M Yamamuro, Joaquim Gama-Rodrigues, Henrique W Pinotti. Effect of Total Parenteral Nutrition with Different Lipid Emulsions on Human Monocyte and Neutrophil Functions. Nutrition 1997;13:128-132
  8. M.J. Ball. Parenteral nutrition in the critically ill: use of a medium chain triglyceride emulsion. Intensive Care Medicine 1993;19:89-95
  9. David F. Driscoll, Marc N. Bacon, Bruce R. Bistrian Physicochemical stability of two Types of Intravenous Lipid Emulsion as Total Nutrient Admixtures Journal of Parenteral and Enteral Nutrition 2000;24(1):15-22
  10. L.A. Horrocks, Y.K. Yeo. Health benefits of docosahexanoic acid (DHA) Pharmacol. Res. 1999;40(3):211-225
  11. Pierre Singer, Mette M. Berger, Greet Van den Berghe, Gianni Biolo, Philip Clader, Alastair Forbes, Richard Griffiths, Georg Kreyman, Xavier Leverve, Claude Pichard, ESPEN Guidelines on Parenteral Nutrition: Intensive Care, Clinical Nutrition 2009;28:387-400
  12. Vera M. Barbosa, Elizabeth E. Miles, Conceicao Calhua, Estevao Lafuente, Philip C. Calder. Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial. Critical Care 2010;14:R5
  13. Grau-Carmona T, Bonet-Saris A, Garcia-de-Lorenzo A, Sanchez-Alvarez C, Rodriguez-Pozo A, Acosta-Escribano J, Minambres E, Herrero-Masesguer JI, Mesejo A ; Influence of n-3 Polyunsaturated Fatty Acids Enriched Lipid Emulsions on Nosocomial Infections and Clinical Outcomes in Critically Ill Patients: ICU Lipids Study; Crit Care Med. 2015 Jan; 43(1):31-9
  14. Matthias W. Wichman, Paul Thul, Hans-Dieter Czarnetzki, Bart J. Morlion, Matthias Kemen, Karl-Walter Jauch. Evaluation of clinical safety and beneficial effects of a fish oil containing lipid emulsion (Lipoplus, MLF541): data from a prospective, randomized, multicenter trial. Critical Care Medicine 2007;35(3):700-706